The South End neighborhood of Boston is next to the city's Back Bay district. The neighborhood is south of Interstate 90 and west of Interstate 93. The area's western boundary goes along Massachusetts Avenue and Southwest Corridor Park. Other major nearby roads include the Mass Avenue Connector and Columbus Avenue.The South End is only 2.5 miles away from downtown Boston. 

The South End is a historic neighborhood that is known for its brick sidewalks, timeless architecture, tree-lined streets and community gardens. The neighborhood is distinguished for its diversity and inclusiveness, as is exemplified through the area's many international restaurants and eclectic art studios. 

Located within the South End is the South of Washington district, shortened to SoWa, which is considered one of Boston's most creative areas. The district is filled with design studios, esoteric shops and modern residential spaces.The SoWa district hosts an open market every Sunday that includes a farmers market, food trucks and booths operated by local artisans. Art studios in the area are open to the public on the first Friday of each month.  

The South End is also home to Boston Medical Center and the Boston University School of Medicine.